Background：This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：Cas Br M （murine） ecotropic retroviral transforming sequence c ,Cas Br M （murine） ectropic retroviral transforming sequence c,Casitas B lineage lymphoma c ,CBL 3,Cbl proto-oncogene C, E3 ubiquitin protein ligase,Cbl proto-oncogene, E3 ubiquitin protein ligase C,CBL SL,E3 ubiquitin-protein ligase CBL-C,RING finger protein 57 ,RNF57,SH3 binding protein CBL C,SH3-binding protein CBL-3,Signal transduction protein CBL C
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CBLC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：23624
Swissprot：Q9ULV8
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
