Background：This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs （SKP1-cullin-F-box）, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes： Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
仕様
Synonyms：beta Transducin Repeat Containing Protein 2,BTRC2,BTRCP2,F-box and WD repeats protein beta-TrCP2,F-box and WD-40 Domain Protein 1B,F-box Protein FBW1B,F-box/WD repeat-containing protein 11,F-box/WD repeat-containing protein 1B,FBW1B,FBW1B,FBXW11,FBXW1B,Homologous to Slimb protein,HOS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human FBXW11
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
