Background：This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：Cancer/testis antigen 31,CT31,Histone demethylase JARID1B,JARID1B,Jumonji AT rich interactive domain 1B,Jumonji/ARID domain-containing protein 1B,Kdm5b,KDM5B,Lysine （K） specific demethylase 5B,Lysine demethylase 5B,Lysine specific demethylase 5B,Lysine-specific demethylase 5B,PLU-1,PLU1,PPP1R98,Protein phosphatase 1 regulatory subunit 98,PUT1,putative DNA/chromatin binding motif,RBBP2H1A,RBP2 like,RBP2-H1,Retinoblastoma-binding protein 2 homolog 1,Retinoblastoma-binding protein 2 homolog 1A
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human KDM5B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10765
Swissprot：Q9UGL1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
