Background：This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：Cytoplasmic protein NCK2,GRB4,Growth factor receptor bound protein 4,NCK adaptor protein 2,Nck-2,NCK2,NCK2,NCKbeta,Non-catalytic region of tyrosine kinase adaptor protein 2,Noncatalytic region of tyrosine kinase beta,SH2/SH3 adaptor protein NCK-beta
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human NCK2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：8440
Swissprot：O43639
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction, Tags ＆ Cell Markers
