Background:This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.
仕様
Synonyms:GC79,LGCR,Transcriptional repressor GATA binding 1,Tricho rhino phalangeal syndrome I,Tricho-rhino-phalangeal syndrome type I protein,Trichorhinophalangeal syndrome I,Trichorhinophalangeal syndrome I homolog,TRPS 1,trpS1,TRPS1 gene,TRPS1,Zinc finger protein GC79,Zinc finger transcription factor TRPS 1,Zinc finger transcription factor Trps1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human TRPS1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):7227
Swissprot:Q9UHF7
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Developmental biology