Background：The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
仕様
Synonyms：AA408962,AA553318,AI844835,Cphn 2,Cphn2,Cyclophilin B,Cyclophilin like protein,CyP 20b,CYP S1,CYP-S1,CYPB,EC 5.2.1.8,MGC14109,MGC2224,OI9,peptidyl prolyl cis trans isomerase B,Peptidyl prolyl cis trans isomerase B precursor,Peptidyl-prolyl cis-trans isomerase B,peptidylprolyl isomerase B （cyclophilin B）,Peptidylprolyl isomerase B,PPIase,PPIase B,Ppib,PPIB,Rotamase,Rotamase B,S cyclophilin,S-cyclophilin,SCYLP
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human PPIB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：5479
Swissprot：P23284
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
