Background：The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
仕様
Synonyms：47 kDa cytokeratin,CK-13,CK13,Cytokeratin 13,Cytokeratin-13,K13,K1C13,Ka13,Keratin 13,Keratin,keratin type I cytoskeletal 13,Keratin-13,Krt-1.13,Krt1-13,KRT13,MGC161462,MGC3781,type I cytoskeletal 13,Type I keratin Ka13,WSN2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human KRT13
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3860
Swissprot：P13646
Isotype：IgG
Research Areas：Cancer, Signal transduction, Tags ＆ Cell Markers
