Background：ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Alpha ETF ,Alpha-ETF,Electron transfer flavoprotein alpha polypeptide ,Electron transfer flavoprotein alpha subunit ,Electron transfer flavoprotein subunit alpha mitochondrial,Electron transfer flavoprotein subunit alpha, mitochondrial,Electron transferring flavoprotein alpha polypeptide,EMA,ETFA,ETFA,GA2,Glutaric aciduria II
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ETFA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：200
Gene_ID（human）：2108
Swissprot：P13804
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
