Background：This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
仕様
Synonyms：Cell death activator CIDE A,Cell Death Inducing DFFA Like Effector A,cell death inducing DNA fragmentation factor, alpha subunit like effector A,CIDE-A,CIDEA
Host：Rabbit
Reactivity：Human
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CIDEA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：100
Gene_ID（human）：1149
Swissprot：O60543
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
