Background:This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
仕様
Synonyms:C4b-binding protein alpha chain,C4bp,C4bpa,C4BPA,Complement component 4 binding protein alpha,Complement component 4 binding protein,Proline-rich protein,PrP,RP11-164O23.4
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human C4BPA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.