Background:This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
仕様
Synonyms:14 3 3 delta,14 3 3 protein zeta/delta,14 3 3 protein/cytosolic phospholipase A2,14 3 3 zeta,14-3-3 protein zeta/delta,1433Z,Epididymis luminal protein 4,Epididymis secretory protein Li 3,HEL S 3,HEL4,KCIP-1,KCIP1,MGC111427,MGC126532,MGC138156,Phospholipase A2,Protein kinase C inhibitor protein 1,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,delta polypeptide,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,zeta,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,zeta polypeptide,Tyrosine 3/tryptophan 5 monooxygenase activation protein,zeta polypeptide,YWHAD,YWHAZ
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:A synthetic peptide of human YWHAZ
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):7534
Swissprot:P63104
Isotype:IgG
Research Areas:Cancer, Cell Biology, Neuroscience, Signal transduction, Tags & Cell Markers