Background：This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element （ChoRE） motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：carbohydrate response element binding protein,bHLHd14,Carbohydrate responsive element binding protein,Class D basic helix-loop-helix protein 14,MIO,MLX interacting protein like,Mlx interactor,MLX-interacting protein-like,MLXIPL,MONDOB,WBS14,WBSCR 14,WBSCR14,Williams Beuren syndrome chromosome region 14,Williams Beuren syndrome chromosome region 14 protein,Williams-Beuren syndrome chromosomal region 14 protein,WS basic helix loop helix leucine zipper protein,WS basic-helix-loop-helix leucine zipper protein,WS bHLH,WS-bHLH
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MLXIPL
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：51085
Swissprot：Q9NP71
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
