Background：This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
仕様
Synonyms：Epididymis secretory protein Li 281,HEL S 281,L lactate dehydrogenase B chain,L-lactate dehydrogenase B chain,Lactate dehydrogenase H chain,LDH B,LDH H,LDH heart subunit,LDH-B,LDH-H,LDHB,LDHB,LDHBD,LDHH,Renal carcinoma antigen NY REN 46,Renal carcinoma antigen NY-REN-46,TRG-5,TRG5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human LDHB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3945
Swissprot：P07195
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
