Background：This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
仕様
Synonyms：MGC130046,MGC130047,MGC57437,NAD dependent deacetylase sirtuin 4,NAD dependent protein deacetylase sirtuin 4,NAD-dependent ADP-ribosyltransferase sirtuin-4,NAD-dependent protein deacetylase sirtuin-4,NAD-dependent protein lipoamidase sirtuin-4,mitochondrial,Regulatory protein SIR2 homolog 4,Silent mating type information regulation 2 homolog,Sir 2 like 4,SIR 2 like protein 4,Sir2 like 4,SIR2 like protein 4,SIR2-like protein 4,SIR2L 4,SIR2L4,SIR4,SIRT 4,Sirt4,Sirtuin （silent mating type information regulation 2 homolog） 4,Sirtuin （silent mating type information regulation 2 homolog） 4 （S. cerevisiae）,Sirtuin 4,Sirtuin type 4,Sirtuin-4,Sirtuin4
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SIRT4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：23409
Swissprot：Q9Y6E7
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
