Background:This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
仕様
Synonyms:Basic helix loop helix PAS protein MOP2,Basic-helix-loop-helix-PAS protein MOP2,bHLHe73,Class E basic helix-loop-helix protein 73,ECYT4,Endothelial PAS domain containing protein 1,Endothelial pas domain protein 1,Endothelial PAS domain-containing protein 1,EPAS 1,EPAS-1,EPAS1,EPAS1,HIF 1 alpha like factor,HIF 2 alpha,HIF-1-alpha-like factor,HIF-2-alpha,HIF2-alpha,HIF2A,HLF,Hypoxia inducible factor 2 alpha,Hypoxia inducible factor 2 alpha subunit,Hypoxia-inducible factor 2-alpha,Member of PAS protein 2,Member of pas superfamily 2,MOP 2,MOP2,PAS domain-containing protein 2,PASD2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human EPAS1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):2034
Swissprot:Q99814
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism