Background：HIV-1, the causative agent of acquired immunodeficiency syndrome （AIDS）, contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element （TAR） located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
仕様
Synonyms：LOQS,Prbp,RISC loading complex subunit TARBP2,RISC-loading complex subunit tarbp2,TAR （HIV 1） RNA binding protein 2,TAR （HIV） RNA binding protein 2,TAR （HIV） RNA-binding protein TRBP1,TAR RNA Binding Protein 2,TAR RNA-binding protein 2,tarbp2,TARBP2 RISC loading complex RNA binding subunit,Trans-activation-responsive RNA-binding protein,TRBP,TRBP1,TRBP2,TRBP2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TARBP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：6895
Swissprot：Q15633
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Microbiology
