Background:This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants.
仕様
Synonyms:HDGF-2,HDGF2,Hdgfrp2,HDGR2,Hepatoma-derived growth factor 2,Hepatoma-derived growth factor,Hepatoma-derived growth factor-related protein 2,heptoma derived growth factor related protein 2 ,HRP-2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human HDGFRP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.