Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
仕様
Synonyms:F box only protein 7,F box protein 7,F-box only protein 7,FBX,FBX07,FBX7,FBX7,Fbxo7,PARK15,PKPS
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human FBXO7
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:200
Gene_ID(human):25793
Swissprot:Q9Y3I1
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling