Background:This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
仕様
Synonyms:17 kDa HBGF-binding protein,17 kDa heparin binding growth factor binding protein ,17 kDa heparin-binding growth factor-binding protein,FGF binding protein 1,FGF BP ,FGF BP1,FGF-binding protein 1,FGF-BP,FGF-BP1,FGFBP ,FGFBP-1,Fgfbp1,FGFP1,Fibroblast growth factor binding protein 1 precursor,Fibroblast growth factor-binding protein 1,HBp17
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human FGFBP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):9982
Swissprot:Q14512
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Signal transduction