Background：This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：2810449N18Rik,AI043036,Mono ADP ribosyltransferase sirtuin 6,NAD-dependent protein deacetylase sirtuin-6,Regulatory protein SIR2 homolog 6,Regulatory protein SIR2 homolog,SIR2 like 6,SIR2 like protein 6,Sir2 related protein type 6,SIR2-like protein 6,SIR2L6,SIR6,SIRT 6,SIRT6,Sirtuin （silent mating type information regulation 2 homolog） 6 （S. cerevisiae）,Sirtuin 6,Sirtuin type 6,Sirtuin6
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of mouse SIRT6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：51548
Swissprot：Q8N6T7
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
