Background：Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
仕様
Synonyms：APG4 autophagy 4 homolog C （S. cerevisiae）,APG4 autophagy 4 homolog C,APG4 C,APG4-C,APG4C,ATG 4C,ATG4 autophagy related 4 homolog C （S. cerevisiae）,ATG4 autophagy related 4 homolog C,Atg4c,ATG4C,AUT （S. cerevisiae） like 1,cysteine endopeptidase,AUT like 1,cysteine endopeptidase （S. cerevisiae）,AUT like 1,cysteine endopeptidase,AUT like 3 cysteine endopeptidase,AUT-like 3 cysteine endopeptidase,AUTL1,AUTL3,Autophagin 3,Autophagin-3,Autophagy related 4C cysteine peptidase,Autophagy related cysteine endopeptidase 3,Autophagy related protein 4 homolog C,Autophagy-related cysteine endopeptidase 3,Autophagy-related protein 4 homolog C,Cysteine protease ATG4C,EC 3.4.22,FLJ14867,OTTHUMP00000010715
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ATG4C
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：84938
Swissprot：Q96DT6
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
