Background：This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase （PI3K） complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：APG6,ATG 6,ATG6,ATG6 autophagy related 6 homolog,Bcl-2-interacting protein beclin,Beclin 1 （coiled coil moesin like BCL2 interacting protein）,Beclin 1 autophagy related,Beclin-1,Beclin1,BECN 1,Becn1,BECN1,Coiled coil myosin like BCL2 interacting protein,Coiled-coil myosin-like BCL2-interacting protein,GT197,Protein GT197,VPS 30,VPS30
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BECN1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：8678
Swissprot：Q14457
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Signal transduction
