Background:The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
仕様
Synonyms:C-t-PAK2,CB422,EC 2.7.11.1,Gamma PAK,Gamma-PAK,hPAK65,Kinase,p21 (CDKN1A) activated kinase 2,p21 (CDKN1A)-activated kinase 2a,p21 activated kinase 2,p21 protein (Cdc42/Rac)-activated kinase 2,p21 protein Cdc42 Rac activated kinase 2,p21-activated kinase 2,p21-activated kinase,65-KD,p21-activated protein kinase I,p21CDKN1A activated kinase 2,p27,p34,p58,p65PAK,PAK 2,PAK-2,PAK-2p34,Pak2,PAK2,PAK65,PAKgamma,S6 H4 kinase,S6/H4 kinase,Serine threonine protein kinase PAK 2,Serine/threonine protein kinase PAK 2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human PAK2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.