Background:This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
仕様
Synonyms:Actin capping protein GCAP39,Actin regulatory protein CAP G,Actin regulatory protein CAP-G,AFCP,Capg,CAPG,Capping actin protein gelsolin like,Capping protein (actin filament) gelsolin like,Capping protein gelsolin like,Epididymis secretory protein Li 66,gCap39,Gelsolin like capping protein,HEL S 66,Macrophage capping protein,Macrophage-capping protein,mbh1,MCP,Myc basic motif homolog 1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human CAPG
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):822
Swissprot:P40121
Isotype:IgG
Research Areas:Cancer, Immunology, Signal transduction