Background：This gene encodes a secreted ligand of the TGF-beta （transforming growth factor-beta） superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 （GDF9）. This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.
仕様
Synonyms：BMP 15,BMP-15,BMP15,BMP15,Bone morphogenetic protein 15,GDF 9B,GDF-9B,GDF9B,Growth/differentiation factor 9B,ODG2,POF4
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human BMP15
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：200
Gene_ID（human）：9210
Swissprot：O95972
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
