Background：The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
仕様
Synonyms：CAAT box DNA binding protein subunit B,CAAT box DNA-binding protein subunit B,CBF A,CBF B,CCAAT binding transcription factor subunit A,HAP 3,HAP3,NF Y protein chain B,NF YB,NF-YB,NFYB,NFYB,Nuclear transcription factor Y beta,Nuclear transcription factor Y subunit B,Nuclear transcription factor Y subunit beta,Transcription factor NF Y B subunit
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human NFYB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：4801
Swissprot：P25208
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
