Background：The protein encoded by this gene is a member of the protein tyrosine phosphatase （PTP） family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
仕様
Synonyms：DKFZp313F1310,FLJ57799,FLJ58245,HPTPE,Protein tyrosine phosphatase epsilon,Protein tyrosine phosphatase receptor type E,Protein tyrosine phosphatase receptor type epsilon,Protein tyrosine phosphatase receptor type epsilon polypeptide,Protein-tyrosine phosphatase epsilon,PTPE,Ptpre,PTPRE,R PTP Epsilon,R-PTP-epsilon,Receptor-type tyrosine-protein phosphatase epsilon
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PTPRE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
