Background:This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
仕様
Synonyms:ARCC2,AW545284,CTPA,CTPP1,CTRCT6,EC 2.7.10.1,Eck,Eph receptor A2,EPHA2,EPHA2,Ephrin receptor,Ephrin receptor EphA2,Ephrin type A receptor 2,Ephrin type-A receptor 2,Epithelial cell kinase,Epithelial cell receptor protein tyrosine kinase,Myk 2,Myk2,Sek 2,Sek2,Soluble EPHA2 variant 1,Tyrosine protein kinase receptor ECK,Tyrosine-protein kinase receptor ECK,Tyrosine-protein kinase receptor MPK-5,Tyrosine-protein kinase receptor SEK-2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human EPHA2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):1969
Swissprot:P29317
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Neuroscience