Background：The protein encoded by this gene belongs to the membrane-associated guanylate kinase （MAGUK） family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain （CARD）. This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
仕様
Synonyms：0610008L17Rik,2410011D02Rik,Bcl10 interacting maguk protein 3,BIMP 3,BIMP3,CAR11,CARD 11,CARD containing MAGUK protein 3,Card maguk protein 1,CARD-containing MAGUK protein 1,CARD11,CARD11 protein,Carma 1,CARMA1,Caspase recruitment domain containing protein 11,Caspase recruitment domain family member 11,Caspase recruitment domain-containing protein 11,MGC133069
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CARD11
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
