Background：The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：2610312E17Rik,Androgen receptor cofactor p44,C79984,HKMT1069,MEP 50,MEP-50,MEP50,MEP50,Methylosome protein 50,MGC2722,Nbla10071,p44,p44/Mep50,RGD1310479 ,RP11 552M11.3,WD repeat containing protein 77,WD repeat domain 77 ,WD repeat-containing protein 77,WDR77
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human WDR77
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200 IF1：50 - 1：100
Gene_ID（human）：79084
Swissprot：Q9BQA1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
