Background：This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signaling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signaling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：4931429D10Rik ,Axin 1 Up-regulated,Axin-1 up-regulated gene 1 protein,CSRN1,CSRNP-1,CSRNP1,Cysteine/serine-rich nuclear protein 1,DKFZp566F164,FAM130B,Protein URAX1,TAIP 3,TAIP-3,TGF beta induced apoptosis protein 3,TGF-beta-induced apoptosis protein 3,URAX1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CSRNP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200 IF1：50 - 1：100
Gene_ID（human）：64651
Swissprot：Q96S65
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
