Background：The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding （PTD） domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
仕様
Synonyms：ARH ,ARH GENE,ARH,ARH1,ARH2,Autosomal recessive hypercholesterolemia protein,DKFZp586D0624,FHCB1,FHCB2,LDL receptor adaptor protein,Ldlrap1,Low density lipoprotein receptor adapter protein 1,MGC34705,OTTHUMP00000008526
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human LDLRAP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：200
Gene_ID（human）：26119
Swissprot：Q5SW96
Isotype：IgG
Research Areas：Cardiovascular, Metabolism, Signal transduction
