Background：The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate （NADP+）, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：10 formyltetrahydrofolate dehydrogenase,10 FTHFDH,10-formyltetrahydrofolate dehydrogenase,10-FTHFDH,AL1L1,Aldehyde dehydrogenase 1 family member L1 ,Aldehyde dehydrogenase family 1 member L1,aldh1l1,Cytosolic 10-formyltetrahydrofolate dehydrogenase,DKFZp781N0997,EC 1.5.1.6,FDH,formyltetrahydrofolate dehydrogenase,FTHFD,OTTHUMP00000155221,OTTHUMP00000214696,OTTHUMP00000214700,OTTHUMP00000222724
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ALDH1L1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10840
Swissprot：O75891
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Neuroscience, Signal transduction
