Background:The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.
仕様
Synonyms:Ab1-210,Cyclophilin 33,Cyclophilin E,Cyclophilin-33,CYP 33,CYP33,EC 5.2.1.8,Peptidyl prolyl cis trans isomerase E,Peptidyl-prolyl cis-trans isomerase E,Peptidylprolyl isomerase E (cyclophilin E),Peptidylprolyl isomerase E,PPIase E,PPIE,PPIE,Rotamase E
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human PPIE
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IP1:50 - 1:200
Gene_ID(human):10450
Swissprot:Q9UNP9
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Signal transduction