Background：The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
仕様
Synonyms：AI225906,AI661148 ,autonomic nervous system and neural crest derivatives-expressed protein 2,Basic helix loop helix transcription factor HAND2,bHLHa26,Class A basic helix-loop-helix protein 26,Deciduum,Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2,DHAND 2,dHAND,DHAND2,Ehand 2,Ehand2,FLJ16260,HAND 2,Hand2,HAND2,Heart and neural crest derivatives expressed 2,Heart and neural crest derivatives expressed protein 2,heart and neural crest derivatives expressed transcript 2,heart,Heart- and neural crest derivatives-expressed protein 2,Hed,Highly similar to dHAND M musculus,MGC125303,MGC125304,Th 2,Th2,Thing 2,Thing2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human HAND2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：9464
Swissprot：P61296
Isotype：IgG
Research Areas：Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience
