Background：This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：DnaJ （Hsp40） homolog subfamily A member 3,DnaJ homolog subfamily A member 3 mitochondrial precursor,DnaJ protein Tid 1,DnaJ protein Tid1,FLJ45758,HCA57,Hepatocellular carcinoma associated antigen 57,Highly similar to HYPOTHETICAL 105.9 KD PROTEIN F22B7.5 IN CHROMOSOME,hTid 1,hTid1,III [Caenorhabditis elegans],TID1,Tumorous imaginal discs （Drosophila） homolog,Tumorous imaginal discs protein Tid56 homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human DNAJA3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：9093
Swissprot：Q96EY1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction
