Background:This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.
仕様
Synonyms:MST092,MST106,MST129,MSTP032,MSTP092,MSTP106,MSTP129,Regulator of G Protein signaling 5,Regulator of G-protein signaling 5,RGS 5,RGS5,RGS5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human RGS5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:IHC1:50 - 1:200
Gene_ID(human):8490
Swissprot:O15539
Isotype:IgG
Research Areas:Cardiovascular, Signal transduction