Background：The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies.
仕様
Synonyms：Transcription factor ZBP-89,Transcription factor ZBP89,ZBP89,Zinc finger DNA binding protein 89,Zinc finger DNA-binding protein 89,Zinc finger protein 148,ZN148,ZNF 148,ZNF148
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human ZNF148
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：1000 IF 1：20 - 1：100
Gene_ID（human）：7707
Swissprot：Q9UQR1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
