Background：Troponin I （TnI）, along with troponin T （TnT） and troponin C （TnC）, is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes： TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 （CMH7） and familial restrictive cardiomyopathy （RCM）.
仕様
Synonyms：cardiac muscle,Cardiac troponin I,cardiomyopathy,dilated 2A （autosomal recessive）,Cardiomyopathy,familial hypertrophic,7,included,CMD1FF,CMD2A,CMH7,cTnI,Familial hypertrophic cardiomyopathy 7,MGC116817,RCM1,Tn1,Tni,TNN I3,TNNC 1,TNNC1,TNNI3,TNNI3,Troponin I,Troponin I cardiac,Troponin I cardiac muscle,Troponin I cardiac muscle isoform,Troponin I type 3 cardiac,troponin I,cardiac 3,TroponinI,Ttroponin I type 3 （cardiac）
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNNI3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：7137
Swissprot：P19429
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
