Background：This gene encodes the protein elongin A, which is a subunit of the transcription factor B （SIII） complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
仕様
Synonyms：Ela1,Elo A,EloA,ELOA1,Elongin 110 kDa subunit,Elongin-A,ElonginA,RNA polymerase II transcription factor SIII subunit A1,SIII,SIII p110,TCEB 3,Tceb3,TCEB3A,Transcription elongation factor B （SIII） polypeptide 3 （110kD）,Transcription elongation factor B （SIII） polypeptide 3,Transcription elongation factor B alpha subunit,Transcription elongation factor B polypeptide 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TCEB3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
