Background：This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：0610042I06Rik,EC 2.7.11.1,FLJ90748,KB 1458E12.1,Kinase responsive to stress 1,KRS1,Mammalian STE20 like protein kinase 2,Mammalian STE20-like protein kinase 2,Mammalian sterile 20-like 2,Mess1,MST,MST-2,MST2,Mst3,Serine/threonine kinase 3 （STE20 homolog, yeast）,Serine/threonine kinase 3 （Ste20, yeast homolog）,Serine/threonine kinase 3,Serine/threonine protein kinase 3,Serine/threonine protein kinase Krs1,Serine/threonine-protein kinase 3,Serine/threonine-protein kinase Krs-1,STE20 like kinase MST2,STE20-like kinase MST2,Stk3,STK3,wu：fc19e11,zgc：55383
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human STK3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：6788
Swissprot：Q13188
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
