Background:This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.
仕様
Synonyms:H1,H1RLX,Preprorelaxin H1,Prorelaxin,Prorelaxin H1,REL1,Relaxin A chain,Relaxin H1,RLN 1,Rln1,RLXH1
Host:Rabbit
Reactivity:Human,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human RLN2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.