Background：This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：G1/S transition control protein binding protein RbAp46,Histone acetyltransferase type B subunit 2,Histone binding protein RBBP7,Histone-binding protein RBBP7,MGC138867,MGC138868,Nucleosome remodeling factor subunit RBAP46,Nucleosome-remodeling factor subunit RBAP46,RBAP46,RBBP 7,RBBP-7,RBBP7,RBBP7,Retinoblastoma binding protein 7,Retinoblastoma binding protein p46,Retinoblastoma-binding protein 7,Retinoblastoma-binding protein p46,Retinoblastoma-binding protein RbAp46
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human RBBP7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IF 1：50 - 1：100 IP 1：50 - 1：200
