Background:The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
仕様
Synonyms:DKFZp686P0638,DKFZp761B2423,E3 ubiquitin-protein ligase RBBP6,MY038,P2P R ,P2PR,p53 associated cellular protein of testis,p53-associated cellular protein of testis,p53-associated cellular protein, testis-derived,PACT,Proliferation potential related protein,Proliferation potential-related protein,Protein P2P R,Protein P2P-R,Protein P2PR,Protein RBQ 1,Protein RBQ1,RB binding protein 6, ubiquitin ligase,RB binding Q protein 1 ,RBBP 6,Rbbp6,RBBP6,RBQ 1,RBQ-1,RBQ1,Retinoblastoma binding protein 6 isoform 3,Retinoblastoma binding Q protein 1,Retinoblastoma-binding protein 6,Retinoblastoma-binding Q protein 1,SNAMA,SNAMA, Drosophila, homolog of
Host:Rabbit
Reactivity:Human
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human RBBP6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.