Background:The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
仕様
Synonyms:DNA repair protein RAD51 homolog 2,hREC2,MGC34245,OTTHUMP00000212251,OTTHUMP00000212253,OTTHUMP00000212254,OTTHUMP00000212255,R51H2,RA51B,RAD51 homolog B (S. cerevisiae),RAD51 homolog B,RAD51 like 1,RAD51 like protein 1,RAD51-like protein 1,Rad51B,RAD51L1,REC2,RecA like protein,Recombination repair protein
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RAD51B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.