Background:In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
仕様
Synonyms:BSAS,Homeo box A1,Homeobox 1F,Homeobox A1,Homeobox protein Hox A1,Homeobox protein Hox-1F,Homeobox protein Hox-A1,Hox 1.6 like protein,Hox 1F,HOX A1,HOX A1 homeodomain protein,HOX1,HOX1F,hoxa1,hoxb1b,HXA1,Lab like protein,MGC45232
Host:Rabbit
Reactivity:Human
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human HOXA1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):3198
Swissprot:P49639
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling