Background：This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
仕様
Synonyms：Factor seven activating protease,Factor seven-activating protease,Factor VII activating protein,Factor VII-activating protease,FSAP,HABP 2,HABP,Habp2,HABP2,Hepatocyte growth factor activator like protein,Hepatocyte growth factor activator-like protein,HGFAL,Hyaluronan binding protein 2,Hyaluronan-binding protein 2 27 kDa light chain alternate form,Hyaluronic acid binding protein 2,PHBP,Plasma hyaluronan binding protein,Plasma hyaluronan-binding protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human HABP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
