Background：The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
仕様
Synonyms：25 kDa FK506-binding protein,25 kDa FKBP,FK506 binding protein 25 T cell,FK506 binding protein 25, T cell, 25-KD,FK506 binding protein 3 （25kD）,FK506-binding protein 3,FKBP 25,FKBP 3,FKBP-25,FKBP-3,FKBP25,FKBP3,FKBP3,Immunophilin FKBP25,Peptidyl-prolyl cis-trans isomerase FKBP3,PPIase,PPIase FKBP3,Rapamycin binding protein,Rapamycin-selective 25 kDa immunophilin,Rotamase
Host：Rabbit
Reactivity：Human
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human FKBP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：2287
Swissprot：Q00688
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
