Background：This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B （CSB） protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome （CS）. CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：CKN1,Cockayne syndrome type A,Cockayne syndrome WD repeat protein CSA,CSA,DNA excision repair protein ERCC-8,DNA excision repair protein ERCC8,ERCC 8,ERCC8,ERCC8,excision repair cross-complementing rodent repair deficiency, complementation group 8
Host：Rabbit
Reactivity：Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human ERCC8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
