Background：This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
仕様
Synonyms：ATOX1,ATOX1,ATX1,ATX1 antioxidant protein 1 homolog （yeast）,ATX1 antioxidant protein 1 homolog,Copper transport protein,Copper transport protein ATOX1,HAH1,Metal transport protein,Metal transport protein ATX1,MGC138453,MGC138455
Host：Rabbit
Reactivity：Human
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human ATOX1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：475
Swissprot：O00244
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction
